Buy Bromazolam Online,Bromazolam is a benzodiazepine derivative drug that is used as a short-term treatment for anxiety. It is a potent and fast-acting drug that can provide relief from symptoms within minutes.

Bromazolam is available for purchase online from us. It is very effective for this purpose but also extremely potent, which means that it is not safe to take if you do not have a prescription.

synthesis Method Bromazolam is synthesized by a process known as “Bromination. This process involves the reaction of a benzodiazepine core with bromine in an organic solvent, such as dimethylformamide (DMF). The bromine reacts with the benzodiazepine core to form a brominated product, which is then purified and isolated.
Synthesis Method Details Design of the Synthesis Pathway
The synthesis pathway for Bromazolam involves the condensation of 2-amino-5-bromo-1,3-thiazole with 2-bromo-2′-chloroacetophenone followed by reduction of the resulting imine with sodium borohydride.

Starting Materials
2-amino-5-bromo-1,3-thiazole, 2-bromo-2′-chloroacetophenone, sodium borohydride, methanol, hydrochloric acid, sodium hydroxide, wate

Reaction
Step 1: Dissolve 2-amino-5-bromo-1,3-thiazole (1.0 g, 4.8 mmol) and 2-bromo-2′-chloroacetophenone (1.3 g, 4.8 mmol) in methanol (20 mL) and add hydrochloric acid (1 M) dropwise until the pH reaches 3., Step 2: Stir the reaction mixture at room temperature for 24 hours., Step 3: Add sodium hydroxide (1 M) dropwise until the pH reaches 10., Step 4: Extract the product with ethyl acetate (3 x 20 mL) and dry the organic layer over anhydrous sodium sulfate., Step 5: Concentrate the organic layer under reduced pressure to obtain a yellow solid., Step 6: Dissolve the yellow solid in methanol (10 mL) and add sodium borohydride (0.5 g, 13.2 mmol) slowly., Step 7: Stir the reaction mixture at room temperature for 24 hours., Step 8: Quench the reaction with water (10 mL) and extract the product with ethyl acetate (3 x 20 mL)., Step 9: Dry the organic layer over anhydrous sodium sulfate and concentrate under reduced pressure to obtain a white solid., Step 10: Recrystallize the white solid from methanol to obtain pure Bromazolam.

Mechanism of Action The mechanism of action of bromazolam is similar to that of other benzodiazepines.When bromazolam binds to the GABA receptor, it results in an increased affinity for GABA, which leads to an increase in GABAergic inhibition of nerve cells in the brain. This inhibition of nerve cells results in a sedative effect.

Biochemical and Physiological Effects The biochemical and physiological effects of bromazolam have been studied extensively in laboratory experiments. The most common effects of bromazolam are sedation, muscle relaxation, and anxiolysis.

CAS RN 71368-80-4
Product Name Bromazolam
Molecular Formula C17H13BrN4
Molecular Weight 353.2 g/mol
IUPAC Name 8-bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine